Metabolomics, Healthy and Disease

DOCUMENT: Application | Ref: 209-200-171Download
Category: Metabolomics, Separation Science Mass Spectrometry, TOF Mass Spectrometry

Metabolomics GCxGC-TOFMS Analysis Comparison of Healthy and Disease States in Zucker Rat Plasma

The linear extracted ion chromatogram, 3D surface plots, and peak table are shown for the derivatized amino acid leucine. The comparison of the pooled lean, fat and obese zucker rat plasma samples highlights the lack of leucine found in the lean sample pool as well as the increasing concentrations found in the fat and obese sample pools. High concentrations of leucine have been studied as indicators in diabetic and obese states of health.